COVID-19

• Lechner M, Chandrasekharan D, Jumani K, Liu J, Gane S, Lund VJ, Philpott C, Jayaraj S. Anosmia as a presenting symptom of SARS-CoV-2 infection in healthcare workers – A systematic review of the literature, case series, and recommendations for clinical assessment and management. Rhinology. 2020 Aug 1;58(4):394-399. (UPSIT)
• Brookes NRG, Fairley JW, Brookes GB. Acute Olfactory Dysfunction-A Primary Presentation of COVID-19 Infection. Ear Nose Throat J. 2020 Aug 6;145561320940119. (UPSIT)
• Moein ST, Hashemian SM, Tabarsi P, Doty RL. Prevalence and reversibility of smell dysfunction measured psychophysically in a cohort of COVID-19 patients. Int Forum Allergy Rhinol. 2020 Aug 6;10.1002/alr.22680. (UPSIT)
• Moein ST, Hashemian SM, Mansourafshar B, Khorram-Tousi A, Tabarsi P, Doty RL. Smell dysfunction: a biomarker for COVID-19. Int Forum Allergy Rhinol. 2020 Aug;10(8):944-950. (UPSIT)
• Tsivgoulis G, Fragkou PC, Delides A, Karofylakis E, Dimopoulou D, Sfikakis PP, Tsiodras S. Quantitative evaluation of olfactory dysfunction in hospitalized patients with Coronavirus [2] (COVID-19). J Neurol. 2020 Aug;267(8):2193-2195. (Q-SIT)
• Lima MA, Silva MTT, Oliveira RV, Soares CN, Takano CL, Azevedo AE, et al. Smell dysfunction in COVID-19 patients: More than a yes-no question. J Neurol Sci. 2020 Aug 26;418:117107. (Q-SIT)
• Prajapati DP, Shahrvini B, MacDonald BV, Crawford KL, Lechner M, DeConde AS, Yan CH. Association of subjective olfactory dysfunction and 12-item odor identification testing in ambulatory COVID-19 patients. Int Forum Allergy Rhinol. 2020 Sep 10. (BSIT)
• Rubel K, Sharma D, Campiti V, Yedlicka G, Burgin SJ, Illing EA, Kroenke K, Ting JY. COVID-19 Status Differentially Affects Olfaction: A Prospective Case-Control Study. OTO Open. 2020 Nov 2;4(4):2473974X20970176. (UPSIT)

2021

• Singer-Cornelius T, Cornelius J, Oberle M, Metternich FU, Brockmeier SJ. Objective gustatory and olfactory dysfunction in COVID-19 patients: a prospective cross-sectional study. Eur Arch Otorhinolaryngol. 2021 Jan 20;1-8. (BSIT)
• Ugurlu BM, Akdogan O, Yilmaz YA, Yapar D, Ugurlu GA, Yerlikaya HS, Felek SA. Quantitative evaluation and progress of olfactory dysfunction in COVID-19. Eur Arch Otorhinolaryngol. 2021 Jan 1. (BSIT)
• Boscolo-Rizzo P, Menegaldo A, Fabbris C, Spinato G, Borsetto D, et al. Six-month psychophysical evaluation of olfactory dysfunction in patients with COVID-19. Chem Senses. 2021 Feb 12;bjab006. (UPSIT)
• Cao AC, Nimmo ZM, Mirza N, Cohen NA, Brody RM, Doty RL. Objective screening for olfactory and gustatory dysfunction during the COVID-19 pandemic: a prospective study in healthcare workers using self-administered testing. World J Otorhinolaryngol Head Neck Surg. 2021 Feb 12. (BSIT)
• Kasiri H, Rouhani N, Salehifar E, Ghazaeian M, Fallah S. Mometasone furoate nasal spray in the treatment of patients with COVID-19 olfactory dysfunction: A randomized, double blind clinical trial. Int Immunopharmacol. 2021 Jun 12;98:107871. (UPSIT)
• Rebholz H, Pfaffeneder-Mantai F, Knoll W, Hassel AW, Frank W, Kleber C. Olfactory dysfunction in SARS-CoV-2 infection: Focus on odorant specificity and chronic persistence. Am J Otolaryngol. Sep-Oct 2021;42(5):103014. (UPSIT)
• Zarabanda D, Vukkadala N, Phillips KM, Qian ZJ, Mfuh KO, Hatter MJ, Lee IT, Rao VK, Hwang PH, Domb G, Patel ZM, Pinsky BA, Nayak JV. The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal SARS-CoV-2 Viral Load: A Randomized Control Trial. Laryngoscope. 2021 Nov 1:10.1002/lary.29935. doi: 10.1002/lary.29935. Epub ahead of print. PMID: 34724213; PMCID: PMC8662040.
• Chu M, Gopikrishna D, Rocke J, Kumar BN. Implementing a COVID-19 specialist smell clinic: experience at the Wrightington, Wigan and Leigh Teaching Hospitals (WWL), NHS Foundation Trust, United Kingdom. Med J Malaysia. 2021 Aug;76(Suppl 4):9-13. PMID: 34558550.
• Bacon DR, Onuorah P, Murr A, Wiesen CA, Oakes J, Thorp BD, Zanation AM, Ebert CS Jr, Wohl D, Senior BA, Kimple AJ. COVID-19 related olfactory dysfunction prevalence and natural history in ambulatory patients. Rhinol Online. 2021;4(4):131-139. doi: 10.4193/rhinol/21.034. Epub 2021 Aug 13. PMID: 34485883; PMCID: PMC8415759.
• Zhu Y, Cao M, Zheng P, Shen W. Residual olfactory dysfunction in coronavirus disease 2019 patients after long term recovery. J Clin Neurosci. 2021 Nov;93:31-35. doi: 10.1016/j.jocn.2021.07.050. Epub 2021 Jul 28. PMID: 34656257; PMCID: PMC8315939.
• Bertlich M, Stihl C, Lüsebrink E, Hellmuth JC, Scherer C, Freytag S, Spiegel JL, Stoycheva I, Canis M, Weiss BG, Ihler F, Haubner F. The course of subjective and objective chemosensory dysfunction in hospitalized patients with COVID-19: a 6-month follow-up. Eur Arch Otorhinolaryngol. 2021 Dec;278(12):4855-4861. doi: 10.1007/s00405-021-06796-4. Epub 2021 Apr 10. PMID: 33837835; PMCID: PMC8035606. (BSIT)
• Leedman SR, Sheeraz M, Sanfilippo PG, Edgar DW, D’Aulerio GV, Robb DM, Richards T, Blyth CC, Mackey DA. Olfactory dysfunction at six months after coronavirus disease 2019 infection. J Laryngol Otol. 2021 Sep;135(9):839-843. doi: 10.1017/S0022215121002085. Epub 2021 Aug 5. PMID: 34348821; PMCID: PMC8367869. (UPSIT)
• Albaharna HA, Alhajjaj AH, Al Shabeb HA, Alghanim DA, Alkhabbaz FL, AlJishi JM. Screening for Olfactory Dysfunction in COVID-19 Patients Using Quick Smell Identification Test. Indian J Otolaryngol Head Neck Surg. 2021 Jun 30:1-7. doi: 10.1007/s12070-021-02709-3. Epub ahead of print. PMID: 34226867; PMCID: PMC8243049. (Q-SIT)
• Wang E, Ulualp SO, Liu C, Veling M. Sudden anosmia and ageusia in a child: A COVID-19 case report. Otolaryngol Case Rep. 2021 Mar;18:100267. doi: 10.1016/j.xocr.2021.100267. Epub 2021 Jan 23. PMID: 34957358; PMCID: PMC7825856. (UPSIT)
• Seo MY, Choi WS, Lee SH. Clinical Features of Olfactory Dysfunction in COVID-19 Patients. J Korean Med Sci. 2021 Jun 7;36(22):e161. doi: 10.3346/jkms.2021.36.e161. PMID: 34100564; PMCID: PMC8185125. (CC-SIT)
• Prajapati DP, Shahrvini B, Said M, Srinivas S, DeConde AS, Yan CH. Assessment of patient recognition of coronavirus disease 2019 (COVID-19)-associated olfactory loss and recovery: a longitudinal study. Int Forum Allergy Rhinol. 2021 Nov;11(11):1529-1537. doi: 10.1002/alr.22820. Epub 2021 Jun 6. PMID: 34096193; PMCID: PMC8222875. (B-SIT)

2022

• Akbari M, Jalali MM, Akbarpour M, Alavi Foumani A, Sharifnia S. Olfactory function trends in COVID-19 patients: a prospective cohort study. Acta Otolaryngol. 2022 Jun;142(6):515-519. doi: 10.1080/00016489.2022.2085326. Epub 2022 Jun 20. PMID: 35723679. (UPSIT-IR)
• Leung JS, Cordano VP, Fuentes-López E, Lagos AE, García-Huidobro FG, Aliaga R, Díaz LA, García-Salum T, Salinas E, Toro A, Callejas CA, Riquelme A, Palmer JN, Medina RA, González G C. Phantosmia May Predict Long-Term Measurable Olfactory Dysfunction After COVID-19. Laryngoscope. 2022 Sep 23:10.1002/lary.30391. doi: 10.1002/lary.30391. Epub ahead of print. PMID: 36149773; PMCID: PMC9538510. (UPSIT)
• Lerner DK, Garvey KL, Arrighi-Allisan AE, Filimonov A, Filip P, Shah J, Tweel B, Del Signore A, Schaberg M, Colley P, Govindaraj S, Iloreta AM. Clinical Features of Parosmia Associated With COVID-19 Infection. Laryngoscope. 2022 Mar;132(3):633-639. doi: 10.1002/lary.29982. Epub 2021 Dec 13. PMID: 34870334; PMCID: PMC9015517. (B-SIT)
• Gitomer SA, Tholen K, Pickett K, Mistry RD, Beswick DM, Kaar JL, Herrmann BW. Olfactory testing as COVID-19 screening in school children; A prospective cross-sectional study. PLoS One. 2022 Nov 22;17(11):e0277882. doi: 10.1371/journal.pone.0277882. PMID: 36413561. (UPSIT)
• Desai DD, Yu SE, Salvatore B, Goldberg Z, Bowers EMR, Moore JA, Phan B, Lee SE. Olfactory and neurological outcomes of SARS-CoV-2 from acute infection to recovery. Front Allergy. 2022 Oct 26;3:1019274. doi: 10.3389/falgy.2022.1019274. PMID: 36389036; PMCID: PMC9644087. (UPSIT)
• Hosseinpoor M, Kabiri M, Rajati Haghi M, Ghadam Soltani T, Rezaei A, Faghfouri A, Poustchian Gholkhatmi Z, Bakhshaee M. Intranasal Corticosteroid Treatment on Recovery of Long-Term Olfactory Dysfunction Due to COVID-19. Laryngoscope. 2022 Nov;132(11):2209-2216. doi: 10.1002/lary.30353. Epub 2022 Aug 25. PMID: 36054369; PMCID: PMC9538270. (UPSIT-Iranian)
• Khan AM, Lee J, Rammaha T, Gupta S, Smith H, Kannampallil T, Farrell N, Kallogjeri D, Piccirillo JF. Natural trajectory of recovery of COVID-19 associated olfactory loss. Am J Otolaryngol. 2022 Sep-Oct;43(5):103572. doi: 10.1016/j.amjoto.2022.103572. Epub 2022 Aug 6. PMID: 35969913; PMCID: PMC9355743. (UPSIT)
• Yus M, Matias-Guiu JA, Gil-Martínez L, Gómez-Ruiz N, Polidura C, Jorquera M, Delgado-Alonso C, Díez-Cirarda M, Matías-Guiu J, Arrazola J. Persistent olfactory dysfunction after COVID-19 is associated with reduced perfusion in the frontal lobe. Acta Neurol Scand. 2022 Aug;146(2):194-198. doi: 10.1111/ane.13627. Epub 2022 Apr 25. PMID: 35467007; PMCID: PMC9111206. (B-SIT)
• Keck JW, Bush M, Razick R, Mohammadie S, Musalia J, Hamm J. Performance of formal smell testing and symptom screening for identifying SARS-CoV-2 infection. PLoS One. 2022 Apr 12;17(4):e0266912. doi: 10.1371/journal.pone.0266912. PMID: 35413084; PMCID: PMC9004758. (PST)
• Monk AS, Bacon DR, Onuorah P, Murr A, Wiesen CA, Oakes J, Thorp BD, Ebert CS Jr, Wohl D, Senior BA, Kimple AJ. A longitudinal study of olfactory dysfunction and parosmia in mild COVID-19 cases. Rhinol Online. 2022;5:168-172. Epub 2022 Nov 12. PMID: 37008801; PMCID: PMC10065456. (BSIT)
• Pires ÍAT, Steffens ST, Mocelin AG, Shibukawa DE, Leahy L, Saito FL, Amadeu NT, Lopes NMD, Garcia ECD, Albanese ML, De Mari LF, Ferreira IM, Veiga CA, Jebahi Y, Coifman H, Fornazieri MA, Hamerschmidt R. Intensive Olfactory Training in Post-COVID-19 Patients: A Multicenter Randomized Clinical Trial. Am J Rhinol Allergy. 2022 Nov;36(6):780-787. doi: 10.1177/19458924221113124. Epub 2022 Jul 21. PMID: 35866202; PMCID: PMC9309586. (UPSIT)
• Gupta S, Lee JJ, Perrin A, Khan A, Smith HJ, Farrell N, Kallogjeri D, Piccirillo JF. Efficacy and Safety of Saline Nasal Irrigation Plus Theophylline for Treatment of COVID-19-Related Olfactory Dysfunction: The SCENT2 Phase 2 Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2022 Sep 1;148(9):830-837. doi: 10.1001/jamaoto.2022.1573. PMID: 35797024; PMCID: PMC9264240. (UPSIT)
• Chen AK, Wang X, McCluskey LP, Morgan JC, Switzer JA, Mehta R, Tingen M, Su S, Harris RA, Hess DC, Rutkowski EK. Neuropsychiatric sequelae of long COVID-19: Pilot results from the COVID-19 neurological and molecular prospective cohort study in Georgia, USA. Brain Behav Immun Health. 2022 Oct;24:100491. doi: 10.1016/j.bbih.2022.100491. Epub 2022 Jul 18. PMID: 35873350; PMCID: PMC9290328. (UPSIT; WETT)
• Hintschich CA, Brosig A, Hummel T, Andorfer KE, Wenzel JJ, Bohr C, Vielsmeier V. Gustatory Function in Acute COVID-19 – Results From Home-Based Psychophysical Testing. Laryngoscope. 2022 May;132(5):1082-1087. doi: 10.1002/lary.30080. Epub 2022 Mar 1. PMID: 35188975; PMCID: PMC9088467. (NHANES PST)

2023

• Yan CH, Jang SS, Lin HC, Ma Y, Khanwalkar AR, Thai A, Patel ZM. Use of platelet-rich plasma for COVID-19-related olfactory loss: a randomized controlled trial. Int Forum Allergy Rhinol. 2023 Jun;13(6):989-997. doi: 10.1002/alr.23116. Epub 2022 Dec 21. PMID: 36507615; PMCID: PMC9877663. (UPSIT)
• Taş BM, Alpaydın T, Akçalı S, Kaygusuz S, Özlük Erol Ö, Şencan Z, Cömert E, Bayar Muluk N, Özel G. Evaluation of Clinical Features and Olfactory Functions in COVID-19: A Multicentre Study. Cureus. 2023 Jun 6;15(6):e40027. doi: 10.7759/cureus.40027. PMID: 37425551; PMCID: PMC10323863. (BSIT)
• Lerner DK, Garvey KL, Arrighi-Allisan A, Kominsky E, Filimonov A, Al-Awady A, Filip P, Liu K, Ninan S, Spock T, Tweel B, van Gerwen M, Schaberg M, Colley P, Del Signore A, Govindaraj S, Iloreta AM. Omega-3 Fatty Acid Supplementation for the Treatment of Persistent COVID-Related Olfactory Dysfunction. Am J Rhinol Allergy. 2023 Sep;37(5):531-540. doi: 10.1177/19458924231174799. Epub 2023 Jun 1. PMID: 37261995. (BSIT)
• Campabadal A, Oltra J, Junqué C, Guillen N, Botí MÁ, Sala-Llonch R, Monté-Rubio GC, Lledó G, Bargalló N, Rami L, Sánchez-Valle R, Segura B. Structural brain changes in post-acute COVID-19 patients with persistent olfactory dysfunction. Ann Clin Transl Neurol. 2023 Feb;10(2):195-203. doi: 10.1002/acn3.51710. Epub 2022 Dec 16. PMID: 36525472; PMCID: PMC9878006. (UPSIT)
• Khan AM, Piccirillo J, Kallogjeri D, Piccirillo JF. Efficacy of Combined Visual-Olfactory Training With Patient-Preferred Scents as Treatment for Patients With COVID-19 Resultant Olfactory Loss: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2023 Feb 1;149(2):141-149. doi: 10.1001/jamaoto.2022.4112. PMID: 36580304; PMCID: PMC9857399. (UPSIT)
• Mahadev A, Hentati F, Miller B, Bao J, Perrin A, Kallogjeri D, Piccirillo JF. Efficacy of Gabapentin For Post-COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2023 Sep 21:e232958. doi: 10.1001/jamaoto.2023.2958. Epub ahead of print. PMID: 37733356; PMCID: PMC10514889. (UPSIT)
• Nawab A, Acosta A, Levine CG, Hoffer ME, Casiano R, Liu XZ. Chemosensory function recovery in COVID-19 patients: A cross-sectional study. Am J Otolaryngol. 2023 Sep 18;45(1):104047. doi: 10.1016/j.amjoto.2023.104047. Epub ahead of print. PMID: 37738881. (UPSIT)
• Peterson AM, Miller BJ, Kallogjeri D, Piccirillo JF, Kukuljan S, Roland LT, Schneider JS, Crock LW, Farrell NF. Stellate Ganglion Block for the Treatment of COVID-19-Induced Olfactory Dysfunction: A Prospective Pilot Study. Otolaryngol Head Neck Surg. 2023 Sep 26. doi: 10.1002/ohn.530. Epub ahead of print. PMID: 37750244. (UPSIT)
• Chan KH, Thomas BJ, Gilbert DD, Tong S, Teynor NJ, Friedman NR, Herrmann BW, Gitomer SA. Olfactory dysfunction and training in children with COVID-19 infection: A prospective study Post-COVID pediatric olfactory training. Int J Pediatr Otorhinolaryngol. 2023 Nov 23;176:111799. doi: 10.1016/j.ijporl.2023.111799. Epub ahead of print. PMID: 38081110. (UPSIT)
• Goljanian Tabrizi A, Mohseni Ashjerdi M, Ghazizadeh M, Maleki M. SARS-Cov-2 Cycle Threshold Value and Olfactory Dysfunction in COVID-19 Patients. Iran J Otorhinolaryngol. 2023 Sep;35(130):263-273. doi: 10.22038/IJORL.2023.71462.3429. PMID: 38090619; PMCID: PMC10712552. (UPSIT)

2024

• Sharetts R, Moein ST, Khan R, Doty RL. Long-Term Taste and Smell Outcomes After COVID-19. JAMA Netw Open. 2024;7(4):e247818. doi:10.1001/jamanetworkopen.2024.7818. (UPSIT, WETT)
• Mohebbi A, Bagheri SH, Raziabadi E, Shafiei A, Roomiani M, Arab M, Dehdari L. Effects of Frequency-Controlled Ear Acupuncture on COVID-19- related Refractory Olfactory Dysfunction: a Randomized Clinical Trial. J Acupunct Meridian Stud. 2024 Apr 30;17(2):69-75. doi: 10.51507/j.jams.2024.17.2.69. PMID: 38686430. (UPSIT)
• Cecchini MP, Pizzini FB, Boschi F, Marcon A, Moro L, Gordon E, Guizard N, Cavedo E, Ricatti MJ, Veronese S, Tamburin S, Tinazzi M, Mansueto G, Sbarbati A. Long-term effects of SARS-CoV-2 infection in patients with and without chemosensory disorders at disease onset: a psychophysical and magnetic resonance imaging exploratory study. Neurol Sci. 2024 Jun;45(6):2409-2418. doi: 10.1007/s10072-024-07429-4. Epub 2024 Mar 5. PMID: 38441790; PMCID: PMC11082021. (UPSIT)
• Filiz G, Bérubé S, Demers C, Cloutier F, Chen A, Pek V, Hudon É, Bolduc-Bégin J, Frasnelli J. Can Multisensory Olfactory Training Improve Olfactory Dysfunction Caused by COVID-19? Multisens Res. 2024 Jul 3:1-18. doi: 10.1163/22134808-bja10127. Epub ahead of print. PMID: 39043376. (UPSIT)
• Garcia ECD, Rosa LR, Santos ACRD, Ishimatsu GKA, Lopes NMD, Fornazieri MA. Investigating the efficacy of melatonin, topical sodium citrate, and multivitamin with zinc as a potential treatment for postinfectious loss of smell. Braz J Otorhinolaryngol. 2024 Aug 31;90(6):101496. doi: 10.1016/j.bjorl.2024.101496. Epub ahead of print. PMID: 39243697. (UPSIT)
• Minichetti DG, Boyd A, Lemire E, Hacker J, Haber AL, Roditi RE, Albers MW, Lee S, Buchheit KM, Laidlaw TM, Bankova LG. Determinants of persistence and recovery of chronic coronavirus disease 2019 chemosensory dysfunction. J Allergy Clin Immunol. 2024 Sep 11:S0091-6749(24)00913-8. doi: 10.1016/j.jaci.2024.08.027. Epub ahead of print. PMID: 39270802. (UPSIT, WETT-SA)
• Gautier SCZ, Coneti V, Horton DB, Greenberg P, Andrews T, Barrett ES, Carson JL, Blaser MJ, Panettieri RA Jr, Rawal S. Long-term recovery of taste and smell following acute COVID-19 infection in a New Jersey cohort. Sci Talks. 2024 Sep;11:100390. doi: 10.1016/j.sctalk.2024.100390. Epub 2024 Aug 15. PMID: 39308483; PMCID: PMC11414579. (NHANES)
• Chiang YF, Jiang RS. Effect of oral zinc and steroids on long COVID hyposmia and hypogeusia. SAGE Open Med. 2024 Nov 26;12:20503121241301894. doi: 10.1177/20503121241301894. PMID: 39611127; PMCID: PMC11603462. (UPSIT-TC, WETT)
• Chowdary H, Riley N, Patel P, Gossweiler AG, Running CA, Srinivasan M. Reduced Salivary Gustin and Statherin in Long-COVID Cohort with Impaired Bitter Taste. J Clin Med. 2024 Nov 13;13(22):6816. doi: 10.3390/jcm13226816. PMID: 39597960; PMCID: PMC11594764. (WETT)