Alzheimer's Disease - Sensonics International

1987

Doty RL, Reyes PF, Gregor T. Presence of both odor identification and detection deficits in Alzheimer’s disease. Brain Res Bull; 1987 May; 18(5): 597-600. (UPSIT)

1991

Serby M, Larson P, Kalkstein D. The nature and course of olfactory deficits in Alzheimer’s disease. Am J Psychiatry. 1991 Mar; 148(3): 357-60. (UPSIT)
Doty RL, Perl DP, Steele JC, Chen KM, Pierce JD Jr, Reyes P, Kurland LT. Odor identification deficit of the parkinsonism-dementia complex of Guam: equivalence to that of Alzheimer’s and idiopathic Parkinson’s disease. Neurology. 1991 May;41(5 Suppl 2):77-80; discussion 80-1. doi: 10.1212/wnl.41.5_suppl_2.77. PMID: 2041598. (UPSIT)

1997

Moberg PJ, Doty RL, Mahr RN, Mesholam RI, Arnold SE, Turetsky BI, Gur RE. Olfactory identification in elderly schizophrenia and Alzheimer’s disease. Neurobiol Aging. 1997 Mar-Apr; 18(2): 163-7. (UPSIT)

1998

Hawkes CH, Shephard BC. Olfactory evoked responses and identification tests in neurological disease. Ann NY Acad Sci. 1998 Nov 30; 855: 608-15. (UPSIT)
Solomon GS, Petrie WM, Hart JR, Brackin HB Jr. Olfactory dysfunction discriminates Alzheimer’s dementia from major depression. J Neuropsychiat Clin Neurosci. 1998 Winter; 10(1): 64-67. (PST)

1999

Graves AB, Bowen JD, Rajaram L, McCormick WC, McCurry SM, Schellenberg GD, Larson EB. Impaired olfaction as a marker for cognitive decline: interaction with apolipoprotein E epsilon4 status. Neurology. 1999 Oct 22; 53(7): 1480-87. (CC-SIT)

2000

McCaffrey RJ, Duff K, Solomon GS. Olfactory dysfunction discriminates probable Alzheimer’s dementia from major depression: A cross validation and extension. J Neuropsychiat Clin Neurosci. 2000 Winter; 12(1): 29-33, 200. (PST)
Devanand DP, Michaels-Marston KS, Liu X, Pelton GH, Padilla M, Marder K, Bell K, Stern Y, Mayeux R. Olfactory deficits in patients with mild cognitive impairment predict Alzheimer’s disease at follow-up. Am J Psychiatry. 2000 Sep;157(9):1399-405. doi: 10.1176/appi.ajp.157.9.1399. PMID: 10964854. (UPSIT)

2001

Gray, AJ, Staples, V, Murren, K, Dhariwal, A & Bentham, P. Olfactory identification is impaired in clinic-based patients with vascular dementia and senile dementia of Alzheimer type. Int J Geriat Psychiatry. 2001 May; 16: 513-17. (UPSIT)

2002

Royall, DR, Chiodo, LK, Polk, MS & Jaramillo, CJ. Severe dysosmia is specifically associated with Alzheimer-like memory deficits in nondemented elderly retirees. Neuroepidemiology. 2002 Mar-Apr; 21: 68-73. (UPSIT)
Swan GE, Carmelli D. Impaired olfaction predicts cognitive decline in nondemented older adults. Neuroepidemiology. 2002 Mar-Apr; 21(2): 58-67. (BSIT)
Duff, K, McCaffrey, RJ & Solomon, GS. The Pocket Smell Test: successfully discriminating probable Alzheimer’s dementia from vascular dementia and major depression. J Neuropsychiat Clin Neurosci. 2002 Spring; 14(2): 197-201. (PST).
Lange R, Donathan CL, Hughes LF. Assessing olfactory abilities with the University of Pennsylvania smell identification test: a Rasch scaling approach. J Alzheimers Dis. 2002 Apr; 4(2): 77-91. (UPSIT)
Wang QS, Tian L, Huang YL, Qin S, He LQ, Zhou JN. Olfactory identification and apolipoprotein E epsilon 4 allele in mild cognitive impairment. Brain Res. 2002 Sep; 951(1): 77-81. (CC-SIT)

2004

Suzuki Y, Yamamoto S, Umegaki H, Onishi J, Mogi N, Fujishiro H, Iguchi A. Smell identification test as an indicator for cognitive impairment in Alzheimer’s disease. Int J Geriatr Psychiatry. 2004 Aug; 19(8): 727-33. (CC-SIT, PST)

2005

Tabert MH, Liu X, Doty RL, Serby M, Zamora D, Pelton GH, Marder K, Albers MW, Stern Y, Devanand DP. A 10-item smell identification scale related to risk for Alzheimer’s disease. Ann Neurol. 2005 Jul; 58(1): 155-60. (UPSIT)
Salerno-Kennedy R, Cusack S, Cashman KD. Olfactory function in people with genetic risk of dementia. Ir J Med Sci. 2005 Oct-Dec; 174(4): 46-50. (B-SIT).
Sparks DL, Petanceska S, Sabbagh M, et al. Cholesterol, copper and Abeta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT). Current Alzheimer Research. 2005 Dec; 2(5): 527-39. (UPSIT)

2007

Wilson RS, Arnold SE, Schneider JA, Tang Y, Bennett DA. The relationship between cerebral Alzheimer’s disease pathology and odour identification in old age. J Neurol Neurosurg Psychiatry. 2007 Jan; 78(1): 30-5. (B-SIT).
Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA. Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry. 2007 Jul; 64(7): 802-8. (B-SIT)
Kjelvik G, Sando SB, Aasly J, Engedal KA, White LR. Use of the Brief Smell Identification Test for olfactory deficit in a Norwegian population with Alzheimer’s disease. Int J Geriatr Psychiatry. 2007 Oct; 22(10): 1020-4. (B-SIT).

2008

Westervelt HJ, Bruce JM, Coon WG, Tremont G. Odor identification in mild cognitive impairment subtypes. J Clin Exp Neuropsychol. 2008 Feb; 30(2): 151-6. (B-SIT).
Devanand DP, Liu X, Tabert MH, Pradhaban G, Cuasay K, Bell K, de Leon MJ, Doty RL, Stern Y, Pelton GH. Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer’s disease. Biol Psychiatry. 2008 Nov 15; 64(10): 871-9. (UPSIT)
Djordjevic J, Jones-Gotman M, De Sousa K, Chertkow H. Olfaction in patients with mild cognitive impairment and Alzheimer’s disease. Neurobiol Aging. 2008 May;29(5):693-706. doi: 10.1016/j.neurobiolaging.2006.11.014. Epub 2007 Jan 17. PMID: 17207898. (UPSIT)
McLaughlin NC, Westervelt HJ. Odor identification deficits in frontotemporal dementia: a preliminary study. Arch Clin Neuropsychol. 2008 Jan;23(1):119-23. doi: 10.1016/j.acn.2007.07.008. Epub 2007 Sep 17. PMID: 17875380. (BSIT)

2009

Jungwirth S, Zehetmayer S, Bauer P, Weissgram S, Tragl KH, Fischer P. Screening for Alzheimer’s dementia at age 78 with short psychometric instruments. Int Psychogeriatr. 2009 Jun; 21(3): 548-59. (PST).
Wilson RS, Arnold SE, Schneider JA, Boyle PA, Buchman AS, Bennett DA. Olfactory impairment in presymptomatic Alzheimer’s disease. Ann N Y Acad Sci. 2009 Jul; 1170: 730-5. (B-SIT).
Velayudhan L, Lovestone S. Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil. J Clin Psychopharmacol. 2009 Aug; 29(4): 387-90. (UPSIT)
Chou KL, Bohnen NI. Performance on an Alzheimer-selective odor identification test in patients with Parkinson’s disease and its relationship with cerebral dopamine transporter activity. Parkinsonism Relat Disord. 2009 Nov; 15(9): 640-3. (UPSIT)
Wang J, Eslinger PJ, Doty RL, Zimmerman EK, Grunfeld R, Sun X, Meadowcroft MD, Connor JR, Price JL, Smith MB, Yang QX. Olfactory deficit detected by fMRI in early Alzheimer’s disease. Brain Res, Oct 21; 1357: 184-94. (UPSIT)

2010

Schmitt AL, Livingston RB, Reese EM, Davis KM.The relationship between the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and olfaction in patients referred for a dementia evaluation. Appl Neuropsychol. 2010 Jul;17(3):163-71. doi: 10.1080/09084281003715667. (UPSIT)
Wong KK, Muller ML, Kuwabara H, Studenski SA, Bohnen NI. Olfactory loss and nigrostriatal dopaminergic denervation in the elderly. Neurosci Lett. 2010 Nov 5; 484(3): 163-7. (UPSIT)
Bahar-Fuchs A, Chételat G, Villemagne VL, Moss S, Pike K, Masters CL, Rowe C, Savage G. Olfactory deficits and amyloid-β burden in Alzheimer’s disease, mild cognitive impairment, and healthy aging: a PiB PET study. J Alzheimers Dis. 2010;22(4):1081-7. doi: 10.3233/JAD-2010-100696. PMID: 20930316. (UPSIT)

2011

Makowska I, Kloszewska I, Grabowska A, Szatkowska I, Rymarczyk K. Olfactory deficits in normal aging and Alzheimer’s disease in the polish elderly population. Arch Clin Neuropsychol. 2011 Apr; 26(3): 270-9. (PST)
Bahar-Fuchs A, Moss S, Rowe C, Savage G. Awareness of olfactory deficits in healthy aging, amnestic mild cognitive impairment and Alzheimer’s disease. Int Psychogeriatr. 2011 Sep;23(7):1097-106. doi: 10.1017/S1041610210002371. Epub 2011 Jan 21. PMID: 21251352. (UPSIT)
Tkalčić, M., Spasić, N., Ivanković, M. et al. Odor identification and cognitive abilities in Alzheimer’s disease. Translat.Neurosci. 2, 233–240 (2011). https://doi.org/10.2478/s13380-011-0026-1 (PST)

2012

Alcalay RN, Caccappolo E, Mejia-Santana H, Tang MX, Rosado L, Orbe Reilly M, et al. Cognitive performance of GBA mutation carriers with early-onset PD: The CORE-PD study. Neurology. 2012 Mar 21. (UPSIT)
Schofield PW, Ebrahimi H, Jones AL, Bateman GA, Murray SR. An olfactory ‘stress test’ may detect preclinical Alzheimer’s disease. BMC Neurol. 2012 May 2; 12(1): 24. (UPSIT)

2013

Velayudhan L, Pritchard M, Powell JF, Proitsi P, Lovestone S. Smell identification function as a severity and progression marker in Alzheimer’s disease. Int Psychogeriatr. 2013 Apr 19:1-10. (UPSIT)

2014

Doty RL, Kamath V. The influences of age on olfaction: a review. Front Psychol. 2014 Feb 7;5:20. doi: 10.3389/fpsyg.2014.00020. eCollection 2014.
Doty RL, Bayona EA, Leon-Ariza DS, Cuadros J, Chung I, Vazquez B, Leon-Sarmiento FE. The lateralized smell test for detecting Alzheimer’s disease: failure to replicate.J Neurol Sci. 2014 May 15;340(1-2):170-3. doi: 10.1016/j.jns.2014.03.022. Epub 2014 Mar 19.(UPSIT).
Kjelvik G, Saltvedt I, White LR, Stenumgård P, Sletvold O, Engedal K, Skåtun K, Lyngvær AK, Steffenach HA, Håberg AK. The brain structural and cognitive basis of odor identification deficits in mild cognitive impairment and Alzheimer’s disease. BMC Neurol. 2014 Aug 26;14:168. doi: 10.1186/s12883-014-0168-1. (BSIT)
Schofield PW, Finnie S, Yong YM. The role of olfactory challenge tests in incipient dementia and clinical trial design. Curr Neurol Neurosci Rep. 2014 Sep;14(9):479. doi: 10.1007/s11910-014-0479-z.

2015

Devanand DP, Lee S, Manly J, Andrews H, Schupf N, Doty RL, Stern Y, Zahodne LB, Louis ED, Mayeux R. Olfactory deficits predict cognitive decline and Alzheimer dementia in an urban community. Neurology. 2015 Jan 13;84(2):182-9. doi: 10.1212/WNL.0000000000001132. Epub 2014 Dec 3. (UPSIT).
Calderón-Garcidueñas L, Mora-Tiscareño A, Franco-Lira M, Zhu H, Lu Z, Solorio E, Torres-Jardón R, D’Angiulli A. Decreases in Short Term Memory, IQ, and Altered Brain Metabolic Ratios in Urban Apolipoprotein ε4 Children Exposed to Air Pollution. J Alzheimers Dis. 2015;45(3):757-70. doi: 10.3233/JAD-142685. PMID: 25633678. (UPSIT)
Velayudhan L, Gasper A, Pritchard M, Baillon S, Messer C, Proitsi P. Pattern of Smell Identification Impairment in Alzheimer’s Disease. J Alzheimers Dis. 2015;46(2):381-7. doi: 10.3233/JAD-142838. PMID: 25757648. (UPSIT)
Growdon ME, Schultz AP, Dagley AS, Amariglio RE, Hedden T, Rentz DM, Johnson KA, Sperling RA, Albers MW, Marshall GA. Odor identification and Alzheimer disease biomarkers in clinically normal elderly. Neurology. 2015 May 26;84(21):2153-60. doi: 10.1212/WNL.0000000000001614. Epub 2015 May 1. PMID: 25934852; PMCID: PMC4451046. (UPSIT)
Yoon JH, Kim M, Moon SY, Yong SW, Hong JM. Olfactory function and neuropsychological profile to differentiate dementia with Lewy bodies from Alzheimer’s disease in patients with mild cognitive impairment: A 5-year follow-up study. J Neurol Sci. 2015 Aug 15;355(1-2):174-9. doi: 10.1016/j.jns.2015.06.013. Epub 2015 Jun 10. (BSIT)
Roberts RO, Christianson TJ, Kremers WK, Mielke MM, Machulda MM, Vassilaki M, Alhurani RE, Geda YE, Knopman DS, Petersen RC. Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia. JAMA Neurol. 2016 Jan;73(1):93-101. doi: 10.1001/jamaneurol.2015.2952. Erratum in: JAMA Neurol. 2016 Apr;73(4):481. PMID: 26569387; PMCID: PMC4710557. (BSIT)

2016

Orasji SS, Mulder JL, de Bruijn SF, Wirtz PW. Olfactory dysfunction in behavioral variant frontotemporal dementia. Clin Neurol Neurosurg. 2016 Feb;141:106-10. doi: 10.1016/j.clineuro.2016.01.003. Epub 2016 Jan 7. PMID: 26773700. (BSIT)
Markopoulou K, Chase BA, Robowski P, Strongosky A, Narożańska E, Sitek EJ, Berdynski M, Barcikowska M, Baker MC, Rademakers R, Sławek J, Klein C, Hückelheim K, Kasten M, Wszolek ZK. Assessment of Olfactory Function in MAPT-Associated Neurodegenerative Disease Reveals Odor-Identification Irreproducibility as a Non-Disease-Specific, General Characteristic of Olfactory Dysfunction. PLoS One. 2016 Nov 17;11(11):e0165112. doi: 10.1371/journal.pone.0165112. eCollection 2016. (UPSIT,BSIT)
Devanand DP. Olfactory Identification Deficits, Cognitive Decline, and Dementia in Older Adults. Am J Geriatr Psychiatry. 2016 Dec;24(12):1151-1157. doi: 10.1016/j.jagp.2016.08.010. Epub 2016 Aug 17. (UPSIT)
Westervelt HJ, Bruce JM, Faust MA. Distinguishing Alzheimer’s disease and dementia with Lewy bodies using cognitive and olfactory measures. Neuropsychology. 2016 Mar;30(3):304-11. doi: 10.1037/neu0000230. Epub 2015 Aug 17. PMID: 26280301. (BSIT)

2017

Passler JS, Doty RL, Dolske MC, St Louis PG, Basignani C, Pepe JW, Bushnev S. Olfactory ability in normal pressure hydrocephalus as compared to Alzheimer’s disease and healthy controls. J Neurol Sci. 2017 Jan 15;372:217-219. doi: 10.1016/j.jns.2016.11.049. Epub 2016 Nov 22. (UPSIT)
Yaffe K, Freimer D, Chen H, Asao K, Rosso A, Rubin S, Tranah G, Cummings S, Simonsick E. Olfaction and risk of dementia in a biracial cohort of older adults. Neurology. 2017 Jan 31;88(5):456-462. doi: 10.1212/WNL.0000000000003558. Epub 2016 Dec 30. (BSIT)
Woodward MR, Amrutkar CV, Shah HC, Benedict RH, Rajakrishnan S, Doody RS, Yan L, Szigeti K. Validation of olfactory deficit as a biomarker of Alzheimer disease. Neurol Clin Pract. 2017 Feb;7(1):5-14. doi: 10.1212/CPJ.0000000000000293. (UPSIT)
Vassilaki M, Christianson TJ, Mielke MM, Geda YE, Kremers WK, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Roberts RO. Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals. Ann Neurol. 2017 Jun;81(6):871-882. doi: 10.1002/ana.24960. Epub 2017 Jun 9. PMID: 28543731; PMCID: PMC5517772. (BSIT)
Woodward MR, Dwyer MG, Bergsland N, Hagemeier J, Zivadinov R, Benedict RH, Szigeti K. Olfactory identification deficit predicts white matter tract impairment in Alzheimer’s disease. Psychiatry Res. 2017 Aug 30;266:90-95. doi: 10.1016/j.pscychresns.2017.06.004. Epub 2017 Jun 9. (UPSIT)
Doty RL. Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate? Lancet Neurol. 2017 Jun;16(6):478-488. doi: 10.1016/S1474-4422(17)30123-0. (UPSIT)
Noonan, David. Smell Test May Sniff Out Oncoming Parkinson’s and Alzheimer’s. Scientific American. June 12, 2017 (UPSIT)
Christensen IT, Larsson EM, Holm IE, Nielsen OBF, Andersen S. Olfactory testing in consecutive patients referred with suspected dementia. BMC Geriatr. 2017 Jun 20;17(1):129. doi: 10.1186/s12877-017-0516-2. (PST)
Lafaille-Magnan ME, Poirier J, Etienne P, Tremblay-Mercier J, Frenette J, Rosa-Neto P, Breitner JCS; PREVENT-AD Research Group. Odor identification as a biomarker of preclinical AD in older adults at risk. Neurology. 2017 Jul 25;89(4):327-335. doi: 10.1212/WNL.0000000000004159. Epub 2017 Jun 28. PMID: 28659431; PMCID: PMC5574678. (UPSIT)
Reijs BLR, Ramakers IHGB, Elias-Sonnenschein L, Teunissen CE, Koel-Simmelink M, Tsolaki M, Wahlund LO, Waldemar G, Hausner L, Johannsen P, Vanderstichele H, Verhey F, Devanand DP, Visser PJ. Relation of Odor Identification with Alzheimer’s Disease Markers in Cerebrospinal Fluid and Cognition. J Alzheimers Dis. 2017;60(3):1025-1034. doi: 10.3233/JAD-170564. PMID: 28984603. (BSIT)
Devanand DP, Lentz C, Chunga RE, Ciarleglio A, Scodes JM, Andrews H, Schofield PW, Stern Y, Huey ED, Bell K, Pelton GH. Change in Odor Identification Impairment is Associated with Improvement with Cholinesterase Inhibitor Treatment in Mild Cognitive Impairment. J Alzheimers Dis. 2017;60(4):1525-1531. doi: 10.3233/JAD-170497. PMID: 29081417. (UPSIT)
Risacher SL, Tallman EF, West JD, Yoder KK, Hutchins GD, Fletcher JW, Gao S, Kareken DA, Farlow MR, Apostolova LG, Saykin AJ. Olfactory identification in subjective cognitive decline and mild cognitive impairment: Association with tau but not amyloid positron emission tomography. Alzheimers Dement (Amst). 2017 Sep 23;9:57-66. doi: 10.1016/j.dadm.2017.09.001. eCollection 2017. (UPSIT)
Goette W, Schmitt A, Clark A. Relationship between smell identification testing and the neuropsychological assessment of dementia in community-dwelling adults. Appl Neuropsychol Adult. 2019 May-Jun;26(3):201-214. doi: 10.1080/23279095.2017.1392303. Epub 2017 Nov 28. PMID: 29182360. (UPSIT)
Goette WF, Werry AE, Schmitt AL. The relationship between smell identification and neuropsychological domains: Results from a sample of community-dwelling adults suspected of dementia. J Clin Exp Neuropsychol. 2018 Aug;40(6):595-605. doi: 10.1080/13803395.2017.1399985. Epub 2017 Dec 4. PMID: 29202669. (UPSIT)
Vasavada MM, Martinez B, Wang J, Eslinger PJ, Gill DJ, Sun X, Karunanayaka P, Yang QX. Central Olfactory Dysfunction in Alzheimer’s Disease and Mild Cognitive Impairment: A Functional MRI Study. J Alzheimers Dis. 2017;59(1):359-368. doi: 10.3233/JAD-170310. PMID: 28671131. (UPSIT)
Ward AM, Calamia M, Thiemann E, Dunlap J, Tranel D. Association between olfaction and higher cortical functions in Alzheimer’s disease, mild cognitive impairment, and healthy older adults. J Clin Exp Neuropsychol. 2017 Sep;39(7):646-658. doi: 10.1080/13803395.2016.1253667. Epub 2016 Nov 20. PMID: 27868477. (UPSIT)
Yoo, H. S., and Ye, B. S. (2017). Olfactory dysfunction in Alzheimer-and Lewy body-related cognitive impairment: diagnostic implication and association with cognition and brain atrophy. Alzheimers Dement. 13:P1524. doi: 10.1016/j.jalz.2017.07.654 (BSIT)

2018

Heinrich J, Vidal JS, Simon A, Rigaud AS, Hanon O, Epelbaum J, Viollet C, Duron E. Relationships Between Lower Olfaction and Brain White Matter Lesions in Elderly Subjects with Mild Cognitive Impairment. J Alzheimers Dis. 2018;61(3):1133-1141. doi: 10.3233/JAD-170378. (BSIT)
Park SJ, Lee JE, Lee KS, Kim JS. Comparison of odor identification among amnestic and non-amnestic mild cognitive impairment, subjective cognitive decline, and early Alzheimer’s dementia. Neurol Sci. 2018 Mar;39(3):557-564. doi: 10.1007/s10072-018-3261-1. Epub 2018 Jan 30. PMID: 29383614. (BSIT)
Kreisl WC, Jin P, Lee S, Dayan ER, Vallabhajosula S, Pelton G, Luchsinger JA, Pradhaban G, Devanand DP. Odor Identification Ability Predicts PET Amyloid Status and Memory Decline in Older Adults. J Alzheimers Dis. 2018;62(4):1759-1766. doi: 10.3233/JAD-170960.] (UPSIT)
Woodward MR, Hafeez MU, Qi Q, Riaz A, Benedict RHB, Yan L, Szigeti K; Texas Alzheimer’s Research, Care Consortium. Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer Disease From Aging. Am J Geriatr Psychiatry. 2018 Aug;26(8):835-846. doi: 10.1016/j.jagp.2018.02.008. Epub 2018 Apr 19. PMID: 29858162; PMCID: PMC6086738. (UPSIT)
Knight JE, Bennett DA, Piccinin AM. Variability and Coupling of Olfactory Identification and Episodic Memory in Older Adults. J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):577-584. doi: 10.1093/geronb/gby058. PMID: 29762752; PMCID: PMC7768712. (BSIT)
Velayudhan L, Wilson-Morkeh F, Penney E, Jesu AJM, Baillon S, Brugha T. Smell identification function in early-onset Alzheimer’s disease and mild cognitive impairment. Int Psychogeriatr. 2019 Jul;31(7):1065-1070. doi: 10.1017/S1041610218001503. PMID: 30318025. (UPSIT)
Brenowitz WD, Kaup AR, Lin FR, Yaffe K. Multiple Sensory Impairment Is Associated With Increased Risk of Dementia Among Black and White Older Adults. J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):890-896. doi: 10.1093/gerona/gly264. PMID: 30452551; PMCID: PMC6521912. (BSIT)
Yoo HS, Jeon S, Chung SJ, Yun M, Lee PH, Sohn YH, Evans AC, Ye BS. Olfactory dysfunction in Alzheimer’s disease- and Lewy body-related cognitive impairment. Alzheimers Dement. 2018 Oct;14(10):1243-1252. doi: 10.1016/j.jalz.2018.05.010. Epub 2018 Jun 21. PMID: 29936148. (CC-SIT)

2019

Lu J, Yang QX, Zhang H, Eslinger PJ, Zhang X, Wu S, Zhang B, Zhu B, Karunanayaka PR. Disruptions of the olfactory and default mode networks in Alzheimer’s disease. Brain Behav. 2019 Jul;9(7):e01296. doi: 10.1002/brb3.1296. Epub 2019 Jun 4. PMID: 31165582; PMCID: PMC6625464. (UPSIT)
Yu HL, Chen ZJ, Zhao JW, Duan SR, Zhao JK. Olfactory Impairment and Hippocampal Volume in a Chinese MCI Clinical Sample. Alzheimer Dis Assoc Disord. 2019 Apr-Jun;33(2):124-128. doi: 10.1097/WAD.0000000000000305. (UPSIT)
Devanand DP, Lee S, Luchsinger JA, Andrews H, Goldberg T, Huey ED, Schupf N, Manly J, Stern Y, Kreisl WC, Mayeux R. Intact global cognitive and olfactory ability predicts lack of transition to dementia. Alzheimers Dement. 2020 Feb;16(2):326-334. doi: 10.1016/j.jalz.2019.08.200. Epub 2020 Jan 4. PMID: 31676234; PMCID: PMC7007828. (UPSIT)
Nag S, Yu L, VanderHorst VG, Schneider JA, Bennett DA, Buchman AS, Wilson RS. Neocortical Lewy bodies are associated with impaired odor identification in community-dwelling elders without clinical PD. J Neurol. 2019 Dec;266(12):3108-3118. doi: 10.1007/s00415-019-09540-5. Epub 2019 Sep 18. (BSIT)
Wu X, Geng Z, Zhou S, Bai T, Wei L, Ji GJ, Zhu W, Yu Y, Tian Y, Wang K. Brain Structural Correlates of Odor Identification in Mild Cognitive Impairment and Alzheimer’s Disease Revealed by Magnetic Resonance Imaging and a Chinese Olfactory Identification Test. Front Neurosci. 2019 Aug 14;13:842. doi: 10.3389/fnins.2019.00842. PMID: 31474819; PMCID: PMC6702423.

2020

Bathini P, Foucras S, Dupanloup I, Imeri I, Perna A, Berruex J, Doucey M, Annoni J, Alberi LA. Classifying dementia progression using microbial profiling of saliva. Alzheimers Dement (Amst). 2020 Feb 14;12(1):e12000. (UPSIT)
Knight JE, Bennett DA, Piccinin AM. Variability and Coupling of Olfactory Identification and Episodic Memory in Older Adults. J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):577-584. (BSIT)
Devanand DP, Lee S, Luchsinger JA, Andrews H, Goldberg T, Huey ED, Schupf N, Manly J, Stern Y, Kreisl WC, Mayeux R. Intact global cognitive and olfactory ability predicts lack of transition to dementia. Alzheimers Dement. 2020 Feb;16(2):326-334. doi: 10.1016/j.jalz.2019.08.200. Epub 2020 Jan 4. PMID: 31676234; PMCID: PMC7007828. (BSIT)
Devanand DP, Liu X, Chunga RE, Cohen H, Andrews H, Schofield PW, Stern Y, Huey ED, Choi J, Pelton GH. Odor Identification Impairment and Change with Cholinesterase Inhibitor Treatment in Mild Cognitive Impairment. J Alzheimers Dis. 2020;75(3):845-854. (UPSIT)
Beach TG, Adler CH, Zhang N, Serrano GE, Sue LI, Driver-Dunckley E, et al. Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer’s disease dementia. PLoS One. 2020 Apr 22;15(4):e0231720. (UPSIT)
Buchanan SM, Parker TD, Lane CA, Keshavan A, Keuss SE, Lu K, James SN, et al. Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort. J Neurol. 2020 Jun 24;1-8. (UPSIT)

2021

Sundermann EE, Fields A, Saloner R, Gouaux B, Bharti A, Murphy C, Moore DJ. The utility of olfactory function in distinguishing early stage Alzheimer’s disease from HIV-associated neurocognitive disorder. AIDS. 2020 Nov 26. (UPSIT)
Klein J, Yan X, Johnson A, Tomljanovic Z, Zou J et al. Olfactory Impairment is Related to Tau Pathology and Neuroinflammation in Alzheimer’s Disease. J Alzheimers Dis. 2021 Feb 20. (UPSIT)
Park H, Kim H, Kim S, Cha H. The Association between Olfactory Function and Cognitive Impairment in Older Persons with Cognitive Impairments: A Cross-Sectional Study. Healthcare 2021, 9(4), 399. (UPSIT)
Motter JN, Liu X, Qian M, Cohen HR, Devanand DP. Odor identification impairment and cholinesterase inhibitor treatment in Alzheimer’s disease. Alzheimers Dement (Amst). 2021 Mar 31;13(1):e12158. doi: 10.1002/dad2.12158. PMID: 33816753; PMCID: PMC8010480.
Forsberg, L.K., Syrjanen, J.A., Ferman, T.J., Boeve, B.F., Miyagawa, T., Graff-Radford, N.R., Knopman, D.S., Graff-Radford, J., Savica, R., Savica, R., Jones, D.T., Fields, J.A., Lucas, J.A., Allen, L.A., St. Louis, E.K., Silber, M.H. and Petersen, R.C. (2021), Brief smell identification test performance in RBD, DLB and AD. Alzheimer’s Dement., 17: e055830. https://doi.org/10.1002/alz.055830 (BSIT)
Kudo, R., Mikuniya, Y., Yamauchi, K., Shimizume, N., Kudo, N., Goto, S., Sasaki, A., Ando, M., Takahashi, Y., Iwane, T., Tomiyama, M., Matsubara, A. Predicting future cognitive decline by olfactory testing: a longitudinal study in the Iwaki Health Promotion Project 2016–2017. Hirosaki Medical Journal, 2020-2021, Volume 71, Issue 2-4, Pages 138-145, Released on J-STAGE March 15, 2021, Online ISSN 2434-4656, Print ISSN 0439-1721, https://doi.org/10.32216/hirosakiigaku.71.2-4_138. (mPST)
Nogi S, Uchida K, Maruta J, Kurozumi H, Akada S, Shiba M, Inoue K. Utility of olfactory identification test for screening of cognitive dysfunction in community-dwelling older adults. PeerJ. 2021 Dec 20;9:e12656. doi: 10.7717/peerj.12656. PMID: 35036144; PMCID: PMC8697762. (J-UPSIT)

2022

Kravatz NL, Ayers E, Bennett DA, Verghese J. Olfactory Dysfunction and Incidence of Motoric Cognitive Risk Syndrome: A Prospective Clinical-Pathologic Study. Neurology. 2022 Sep 8;99(17):e1886–96. doi: 10.1212/WNL.0000000000201030. Epub ahead of print. PMID: 36240083; PMCID: PMC9620808. (BSIT)

2023

Papadatos Z, Phillips NA. Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer’s disease. Neurobiol Aging. 2023 Apr 6;128:33-42. doi: 10.1016/j.neurobiolaging.2023.04.001. Epub ahead of print. PMID: 37146503. (BSIT)
Motter JN, Choi J, Lee S, Goldberg TE, Albert S, Devanand DP. Association of Performance on Olfactory and Cognitive Screening Tests With Conversion to Dementia in a Biracial Cohort of Older Adults. Neurology. 2023 Jul 6:10.1212/WNL.0000000000207578. doi: 10.1212/WNL.0000000000207578. Epub ahead of print. PMID: 37414570. (BSIT)
Knight JE, Yoneda T, Lewis NA, Muniz-Terrera G, Bennett DA, Piccinin AM. Transitions Between Mild Cognitive Impairment, Dementia, and Mortality: The Importance of Olfaction. J Gerontol A Biol Sci Med Sci. 2023 Jul 8;78(7):1284-1291. doi: 10.1093/gerona/glad001. PMID: 36611276; PMCID: PMC10329218. (BSIT)
Kalam S, Numbers K, Lipnicki DM, Lam BCP, Brodaty H, Reppermund S. The combination of olfactory dysfunction and depression increases the risk of incident dementia in older adults. Int Psychogeriatr. 2023 Jun 2:1-12. doi: 10.1017/S1041610223000480. Epub ahead of print. PMID: 37264675. (BSIT)
Zhu B, Li Q, Xi Y, Li X, Yang Y, Guo C. Local Brain Network Alterations and Olfactory Impairment in Alzheimer’s Disease: An fMRI and Graph-Based Study. Brain Sci. 2023 Apr 7;13(4):631. doi: 10.3390/brainsci13040631. PMID: 37190596; PMCID: PMC10137180. (UPSIT)
Wang SM, Kang DW, Um YH, Kim S, Lee CU, Lim HK. Olfactory Dysfunction Is Associated with Cerebral Amyloid Deposition and Cognitive Function in the Trajectory of Alzheimer’s Disease. Biomolecules. 2023 Aug 31;13(9):1336. doi: 10.3390/biom13091336. PMID: 37759734; PMCID: PMC10526796. (BSIT)
Yamashita Y, Shoji Y, Yanagimoto H, Morita K, Kodama H, Tsuruhisa Y, Ookawa J. A characteristic of olfactory function in four types of dementia and non-dementia subjects using smell identification test. Psychogeriatrics. 2023 Nov 14. doi: 10.1111/psyg.13036. Epub ahead of print. PMID: 37963486. (PST)
Guo J, Dove A, Wang J, Laukka EJ, Ekström I, Dunk MM, Bennett DA, Xu W. Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study. EBioMedicine. 2023 Dec;98:104862. doi: 10.1016/j.ebiom.2023.104862. Epub 2023 Oct 28. PMID: 38251465; PMCID: PMC10628348. (BSIT)
Liu S, Jiang Z, Zhao J, Li Z, Li R, Qiu Y, Peng H. Disparity of smell tests in Alzheimer’s disease and other neurodegenerative disorders: a systematic review and meta-analysis. Front Aging Neurosci. 2023 Sep 7;15:1249512. doi: 10.3389/fnagi.2023.1249512. PMID: 37744388; PMCID: PMC10512741. (UPSIT, BSIT)

2024

Chao LL. Olfactory and cognitive decrements in 1991 Gulf War veterans with gulf war illness/chronic multisymptom illness. Environ Health. 2024 Jan 30;23(1):14. doi: 10.1186/s12940-024-01058-2. PMID: 38291474; PMCID: PMC10825982. (UPSIT)
Xie B, Yang S, Hao Y, Sun Y, Li L, Guo C, Yang Y. Impaired olfactory identification in dementia-free individuals is associated with the functional abnormality of the precuneus. Neurobiol Dis. 2024 May;194:106483. doi: 10.1016/j.nbd.2024.106483. Epub 2024 Mar 26. PMID: 38527709. (UPSIT)
Coughlin DG, MacLeod KR, Middleton JS, Bozoki AC, Galvin JE, Irwin DJ, Lippa CF, Litvan I, Lopez OL, Berman S, Tsuang DW, Zabetian CP, Honig LS, Marder KS, Fleisher JE, Sabbagh M, Wint D, Taylor AS, Bekris L, Leverenz JB, Galasko D. Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies. Neurology. 2024 Aug 13;103(3):e209656. doi: 10.1212/WNL.0000000000209656. Epub 2024 Jul 16. PMID: 39013126; PMCID: PMC11238940. (UPSIT)

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