Schizophrenia

by Joe Fanelli | Aug 8, 2020

1991

Seidman LJ, Talbot NL, Kalinowski AG, McCarley RW, Faraone SV, Kremen WS, et al. Neuropsychological probes of fronto-limbic system dysfunction in schizophrenia. Olfactory identification and Wisconsin Card Sorting performance. Schizophr Res. 1991 Dec; 6(1): 55-65. (UPSIT)

1993

Wu J, Buchsbaum MS, Moy K, Denlea N, Kesslak P, Tseng H, Plosnaj D, Hetu M, Potkin S, Bracha S, et al. Olfactory memory in unmedicated schizophrenics. Schizophr Res. 1993 Mar;9(1):41-7. (UPSIT)

1994

Houlihan DJ, Flaum M, Arnold SE, Keshavan M, Alliger R. Further evidence for olfactory identification deficits in schizophrenia. Schizophr Res. 1994 May; 12(2): 179-82. (UPSIT)
Kopala LC, Good KP, Honer WG. Olfactory hallucinations and olfactory identification ability in patients with schizophrenia and other psychiatric disorders. Schizophr Res. 1994; 12(3): 205-11.(UPSIT)

1995

Kopala LC, Good K, Honer WG. Olfactory identification ability in pre- and postmenopausal women with schizophrenia. Biol Psychiat. 1995 Jul 1; 38(1): 57-63. (UPSIT)
Kopala L, Good K, Martzke J, Hurwitz T. Olfactory deficits in schizophrenia are not a function of task complexity. Schizophr Res. 1995 Oct;17(2):195-9. doi: 10.1016/0920-9964(94)00085-m. PMID: 8562494. (UPSIT)

1996

Brewer WJ, Edwards J, Anderson V, Robinson T, Pantelis C. Neuropsychological, olfactory, and hygiene deficits in men with negative symptom schizophrenia. Biol Psychiatry. 1996 Nov 15;40(10):1021-31. (UPSIT)

1997

Moberg PJ, Doty RL, Mahr RN, Mesholam RI, Arnold SE, Turetsky BI, Gur RE. Olfactory identification in elderly schizophrenia and Alzheimer’s disease. Neurobiol Aging. 1997 Mar-Apr; 18(2): 163-7. (UPSIT)
Moberg PJ, Doty RL, Turetsky BI, Arnold SE, Mahr RN, Gur RC, Bilker W, Gur RE. Olfactory identification deficits in schizophrenia: correlation with duration of illness. Amer J Psychiat. 1997 Jul; 154(7): 1016-8. (UPSIT) (PIT)
Seidman LJ, Goldstein JM, Goodman JM, Koren D, Turner WM, Faraone SV, Tsuang MT. Sex differences in olfactory identification and Wisconsin Card Sorting performance in schizophrenia: relationship to attention and verbal ability. Biol Psychiatry. 1997 Jul 15;42(2):104-15. doi: 10.1016/S0006-3223(96)00300-9. PMID: 9209727. (UPSIT)

1998

Kopala LC, Good KP, Koczapski AB, Honer WG. Olfactory deficits in patients with schizophrenia and severe polydipsia. Biol Psychiat. 1998; 43(7): 497-502. (UPSIT)
Kopala LC, Good KP, Torrey EF, Honer WG. Olfactory function in monozygotic twins discordant for schizophrenia. Am J Psychiatry. 1998 Jan;155(1):134-6. doi: 10.1176/ajp.155.1.134. PMID: 9433354.
Malaspina D, Perera GM, Lignelli A, Marshall RS, Esser PD, Storer S, Furman V, Wray AD, Coleman E, Gorman JM, Van HR. SPECT imaging of odor identification in schizophrenia. Psychiat Res. 1998 Apr 10; 82: 53-61.
Purdon SE. Olfactory identification and Stroop interference converge in schizophrenia. J Psychiat Neurosci. 1998 May; 23(3): 163-71. (UPSIT)
Stedman TJ, Clair AL. Neuropsychological, neurological and symptom correlates of impaired olfactory identification in schizophrenia. Schizophr Res. 1998 Jun 22; 32(1): 23-30. (UPSIT)
Saoud M, Hueber T, Mandran H, Dalery J, d’Amato T. Olfactory identification deficiency and WCST performance in men with schizophrenia. Psychiat Res. 1998 Nov 16; 81(2): 251-7. (UPSIT)

1999

Striebel KM, Beyerstein B, Remick RA, Kopala L, Honer WG. Olfactory identification and psychosis. Biol Psychiatry. 1999 Jun 1; 45(11): 1419-25. (UPSIT)
Moberg PJ, Agrin R, Gur RE, Gur RC, Turetsky BI, Doty RL. Olfactory dysfunction in schizophrenia: a qualitative and quantitative review. Neuropsychopharmacology. 1999 Sep; 21(3): 325-40. (UPSIT)

2000

Turetsky BI, Moberg, P.J., Yousem DM, Doty RL, Arnold SE, Gur RI. Reduced olfactory bulb volume in patients with schizophrenia. Amer J Psychiatry. 2000 May; 157(5): 828-30.

2001

Clark C, Kopala L, Li DK, Hurwitz T. Regional cerebral glucose metabolism in never-medicated patients with schizophrenia. Can J Psychiatry. 46(4): 340-5 D. Malaspina and E. Coleman. Olfaction and social drive in schizophrenia. Archives of General Psychiatry. 2001 Jun;60 (6): 578-84. (UPSIT)
Kohler, C.G., Moberg, P.J., Gur, R.E. & Doty, R.L. Olfactory dysfunction in schizophrenia and temporal lobe epilepsy. Neuropsychiat Neuropsychol Behav Neurol. 2001 Apr-Jun; 14: 83-8. (UPSIT)
Kopala LC, Good KP, Morrison K, Bassett AS, Alda M, Honer WG. Impaired olfactory identification in relatives of patients with familial schizophrenia. Am J Psychiatry. 2001 Aug; 158(8): 1286-90. (UPSIT)

2002

Coleman E, Goetz RR, Leitman D, Yale S, Stanford A, Gorman JM, Malaspina D. Odor identification impairments in schizophrenia: relationship with demographic measures, clinical variables, and diagnostic subtypes.CNS Spectr. 2002 Jan; 7(1): 43-8.
Good KP, Martzke JS, Milliken HI, Honer WG, Kopala LC. (2002) Unirhinal olfactory identification deficits in young male patients with schizophrenia and related disorders: association with impaired memory function. Schizophr Res. 2002 Aug. 1:56(3): 211-23. (UPSIT)

2003

Turetsky B.I. , Moberg, P.J., K. Owzar, S. C. Johnson, R. L. Doty, and R.E. Gur. Physiologic impairment of olfactory stimulus processing in schizophrenia. Biological Psychiatry. 2003 Mar 1; 53(5): 403-411, 2003.
Goudsmit N, Coleman E, Seckinger RA, Wolitzky R, Stanford AD, Corcoran C, Goetz RR, Malaspina D. A brief smell identification test discriminates between deficit and non-deficit schizophrenia. Psychiatry Res. 2003 Sep 30; 120(2): 155-64. (B-SIT).

2004

McLean D, Féron F, Mackay-Sim A, McCurdy R, Hirning M, Chant D, McGrath J. Paradoxical association between smoking and olfactory identification in psychosis versus controls. Aust N Z J Psychiatry. 2004 Jan-Feb;38(1-2):81-3. doi: 10.1111/j.1440-1614.2004.01301.x. PMID: 14731198. (UPSIT)
Szeszko PR, Bates J, Robinson D, Kane J, Bilder RM. Investigation of unirhinal olfactory identification in antipsychotic-free patients experiencing a first-episode schizophrenia. Schizophr Res. 2004 Apr 1; 67(2-3): 219-25. (UPSIT)
Goudsmit N, Wolitzky R, Seckinger RA, Corcoran C, Stanford A, Rosenfield P, Goetz R, Malaspina D. Trail making and olfaction in schizophrenia: implications for processing speed. CNS Spectr. 2004 May; 9(5): 344-9, 356.

Minor KL, Wright BD, Park S. The Smell Identification Test as a measure of olfactory identification ability in schizophrenia and healthy populations: a Rasch psychometric study. J Abnorm Psychol. , May; 113(2): 207-16. (UPSIT)

Seckinger RA, Goudsmit N, Coleman E, Harkavy-Friedman J, Yale S, Rosenfield PJ, Malaspina D. Olfactory identification and WAIS-R performance in deficit and nondeficit schizophrenia. Schizophr Res. 2004 Jul; 69(1): 55-65. (UPSIT)

2006

Good KP, Whitehorn D, Rui Q, Milliken H, Kopala LC. Olfactory identification deficits in first-episode psychosis may predict patients at risk for persistent negative and disorganized or cognitive symptoms. Am J Psychiatry. 2006 May; 163(5): 932-3. (UPSIT)
Compton MT, McKenzie Mack L, Esterberg ML, Bercu Z, Kryda AD, Quintero L, Weiss PS, Walker EF. Associations between olfactory identification and verbal memory in patients with schizophrenia, first-degree relatives, and non-psychiatric controls. Schizophr Res. 2006 Sep; 86(1-3): 154-66. (UPSIT)

2007

Brewer WJ, Wood SJ, Pantelis C, Berger GE, Copolov DL, McGorry PD. Olfactory sensitivity through the course of psychosis: Relationships to olfactory identification, symptomatology and the schizophrenia odour. Psychiatry Res. 2007 Jan 15; 149(1-3): 97-104.
Moberg PJ, McGue C, Kanes SJ, Roalf DR, Balderston CC, Gur RE, Kohler CG, Turetsky BI. Phenylthiocarbamide (PTC) perception in patients with schizophrenia and first-degree family members: relationship to clinical symptomatology and psychophysical olfactory performance. Schizophr Res. 2007 Feb; 90(1-3): 221-8.
Kohler CG, Barrett FS, Gur RC, Turetsky BI, Moberg PJ. Association between facial emotion recognition and odor identification in schizophrenia. J Neuropsychiatry Clin Neurosci. 2007 Spring; 19(2):128-31.
Turetsky BI, Glass CA, Abbazia J, Kohler CG, Gur RE, Moberg PJ. Reduced posterior nasal cavity volume: a gender-specific neurodevelopmental abnormality in schizophrenia. Schizophr Res. 2007 Jul; 93(1-3): 237-44.
Good KP, Leslie RA, McGlone J, Milliken HI, Kopala LC. Sex differences in olfactory function in young patients with psychotic disorders. Schizophr Res. 2007 Aug 15. (SIT).

2008

Compton MT, Chien VH. No association between psychometrically-determined schizotypy and olfactory identification ability in first-degree relatives of patients with schizophrenia and non-psychiatric controls. Schizophr Res. 2008 Mar; 100(1-3): 216-23. (UPSIT)

2009

Keshavan MS1, Vora A, Montrose D, Diwadkar VA, Sweeney J. Olfactory identification in young relatives at risk for schizophrenia. Acta Neuropsychiatr. 2009 Jun;21(3):121-124. (UPSIT)

2010

Ishizuka K, Tajinda K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test. Neurosci Res, 2010 Jan; 66(1): 106-10. (UPSIT)
Strauss GP, Allen DN, Ross SA, Duke LA, Schwartz J. Olfactory hedonic judgment in patients with deficit syndrome schizophrenia. Schizophr Bull. 2010 Jul; 36(4): 860-8. (B-SIT).

2011

Lee H, Malaspina D, Ahn H, Perrin M, Opler MG, Kleinhaus K, Harlap S, Goetz R, Antonius D. Paternal age related schizophrenia (PARS): Latent subgroups detected by k-means clustering analysis. Schizophr Res. 2011 May; 128(1-3): 143-9. (UPSIT)
Kamath V, Turetsky BI, Moberg PJ. Identification of pleasant, neutral, and unpleasant odors in schizophrenia. Psychiatry Res. 2011 May 15; 187(1-2): 30-5. (UPSIT)
Cumming AG, Matthews NL, Park S. Olfactory identification and preference in bipolar disorder and schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2011 Jun; 261(4): 251-9. (UPSIT)
Kamath V, Bedwell JS, Compton MT. Is the odour identification deficit in schizophrenia influenced by odour hedonics? Cogn Neuropsychiatry. 2011 Sep; 16(5): 448-60, doi:10.1080/13546805.2011.552561. (B-SIT).
Nguyen AD, Pelavin PE, Shenton ME, Chilakamarri P, McCarley RW, Nestor PG, Levitt JJ. Olfactory sulcal depth and olfactory bulb volume in patients with schizophrenia. Brain Imaging Behav. 2011 Dec; 5(4): 252-61. (UPSIT)

2012

Kamath V, Moberg PJ, Gur RE, Doty RL, Turetsky BI. Effects of the val(158)met catechol-O-methyltransferase gene polymorphism on olfactory processing in schizophrenia. Behav Neurosci. 2012 Feb;126(1):209-15. (UPSIT)

2013

Schecklmann M, Schwenck C, Taurines R, Freitag C, Warnke A, Gerlach M, Romanos M. A systematic review on olfaction in child and adolescent psychiatric disorders. J Neural Transm. 2013 Jan;120(1):121-30. doi: 10.1007/s00702-012-0855-2. Epub 2012 Jul 19.
Lee MR, Wehring HJ, McMahon RP, Linthicum J, Cascella N, Liu F, Bellack A, Buchanan RW, Strauss GP, Contoreggi C, Kelly DL. Effects of adjunctive intranasal oxytocin on olfactory identification and clinical symptoms in schizophrenia: Results from a randomized double blind placebo controlled pilot study. Schizophr Res. 2013 Feb 12. pii: S0920-9964(13)00012-1. doi: 10.1016/j.schres.2013.01.001. (UPSIT)
Kamath V, Turetsky BI, Seligman SC, Marchetto DM, Walker JB, Moberg PJ. The influence of semantic processing on odor identification ability in schizophrenia. Arch Clin Neuropsychol. 2013 May; 28(3): 254-61. doi: 10.1093/arclin/act018. (UPSIT)

2014

Lin A, Brewer WJ, Yung AR, Nelson B, Pantelis C, Wood SJ. Olfactory identification deficits at identification as ultra-high risk for psychosis are associated with poor functional outcome. Schizophr Res. 2015 Feb;161(2-3):156-62. doi: 10.1016/j.schres.2014.10.051. Epub 2014 Dec 1. PMID: 25476117. (UPSIT)
Gill KE, Evans E, Kayser J, Ben-David S, Messinger J, Bruder G, Malaspina D, Corcoran CM. Smell identification in individuals at clinical high risk for schizophrenia. Psychiatry Res. 2014 Dec 15;220(1-2):201-4. doi: 10.1016/j.psychres.2014.07.018. Epub 2014 Jul 17. (UPSIT)

2015

Strauss GP, Keller WR, Koenig JI, Gold JM, Ossenfort KL, Buchanan RW. Plasma oxytocin levels predict olfactory identification and negative symptoms in individuals with schizophrenia. Schizophr Res. 2015 Mar;162(1-3):57-61. doi: 10.1016/j.schres.2014.12.023. Epub 2015 Jan 9. (UPSIT)

2016

Kotlicka-Antczak M, Pawełczyk A, Karbownik MS, Pawełczyk T, Strzelecki D, Żurner N, Urban-Kowalczyk M. Deficits in the identification of pleasant odors predict the transition of an at-risk mental state to psychosis. Schizophr Res. 2017 Mar;181:49-54. doi: 10.1016/j.schres.2016.10.019. Epub 2016 Oct 17. PMID: 27765522. (UPSIT)
Urban-Kowalczyk M, Śmigielski J, Strzelecki D. Olfactory identification in patients with schizophrenia – the influence of β-endorphin and calcitonin gene-related peptide concentrations. Eur Psychiatry. 2017 Mar;41:16-20. doi: 10.1016/j.eurpsy.2016.09.004. Epub 2017 Feb 3. PMID: 28049076. (UPSIT)

2017

Urban-Kowalczyk M, Śmigielski J, Strzelecki D. Olfactory identification in patients with schizophrenia – the influence of β-endorphin and calcitonin gene-related peptide concentrations. Eur Psychiatry. 2017 Mar;41:16-20. (UPSIT)

2018

Mossaheb N, Kaufmann RM, Schlögelhofer M, Aninilkumparambil T, Himmelbauer C, Gold A, Zehetmayer S, Hoffmann H, Traue HC, Aschauer H. The Impact of Sex Differences on Odor Identification and Facial Affect Recognition in Patients with Schizophrenia Spectrum Disorders. Front Psychiatry. 2018 Jan 31;9:9. doi: 10.3389/fpsyt.2018.00009. eCollection 2018. (UPSIT)
Urban-Kowalczyk M, Śmigielski J, Kotlicka-Antczak M. Overrated hedonic judgment of odors in patients with schizophrenia. CNS Neurosci Ther. 2018 Dec;24(12):1156-1162. doi: 10.1111/cns.12849. Epub 2018 Apr 11. PMID: 29638031; PMCID: PMC6489818. (UPSIT)
Zou LQ, Zhou HY, Lui SSY, Wang Y, Wang Y, Gan J, Zhu XZ, Cheung EFC, Chan RCK. Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Apr 20;83:137-141. doi: 10.1016/j.pnpbp.2018.01.014. Epub 2018 Jan 31. (UPSIT)

2019

Urban-Kowalczyk M, Strzelecki D, Śmigielski J, Kotlicka-Antczak M. Odor perception and hedonics in chronic schizophrenia and in first episode psychosis. Neuropsychiatr Dis Treat. 2019 Mar 5;15:647-654. doi: 10.2147/NDT.S192523. eCollection 2019. (UPSIT)

2020

Ver Loren van Themaat AH, Uddin MJ, Christiani CJ, Hemager N, Ellersgaard D, et al. Odor identification in 7-year-old children at familial high risk of schizophrenia or bipolar disorder – the Danish high risk and resilience study VIA 7. Schizophr Res. 2020 Feb;216:77-84. (B-SIT)
Lui SSY, Chiu MWY, Chui WWH, Wong JOY, Man CMY, Cheung EFC, Chan RCK. Impaired olfactory identification and hedonic judgment in schizophrenia patients with prominent negative symptoms. Cogn Neuropsychiatry. 2020 Mar;25(2):126-138. (UPSIT)
Li ZT, Li SB, Wen JF, Zhang XY, Hummel T, Zou LQ. Early-Onset Schizophrenia Showed Similar but More Severe Olfactory Identification Impairment Than Adult-Onset Schizophrenia. Front Psychiatry. 2020 Jun 30;11:626. (UPSIT)